i usually drew with a 23, shot with a 25. Did delt delt quad quad, repeat.
drawing with anything greater than a 20 just takes awhile. Usually took about 20-30 seconds just to draw up. Remember to pull the cylinder back to the amount and inject the air into the vial to get a vacuum going.
as for the soreness, rub it down or take a hot shower immediately after, it helps, ALOT.