Metformin regular vs. extended release

[MR. BMJ]

Anybody tell a difference between the two? I've been taking Glycomet-SR that past month and seems decent. I haven't used the regular Met since the 90's so it's hard to gauge the comparison. I know they are both met, just wondering if you guys preferred one over the other?

Taking 500mg in the am, then the second dose at night.

:headbang::action-smiley-030::action-smiley-055:

 

[A_Roughneck_S]

There should be no difference between the two, besides the theoretical risk of hypoglycemia (higher with the shorter-acting immediate-release vs the sustained release). It is also a technical possibility that individuals may respond differently to the inert ingredients (i.e. excipients) that may differ among the generic/brand manufacturers.

Also, if you are taking the extended/sustained release formulation, you should be dosing this more conveniently once a day, since the release pattern of the drug happens over a 24-hour period. For you, this would likely be 1000mg in the AM. Only the immediate release formulation requires twice daily dosing.

 

[Whey2Heavy]

The only real difference between the two IMO is in relation to possible gastric issues. The normal version is notorious for issues like diarrhea, gas, etc. but the extended release seems to be a bit easier for people to handle.

 

[Caveman5]

I use the gyclomet as well. Never tried E.R. version...what are your guys thoughts on only taking it before carb meals instead of the standard 1 dose in a.m 1 dose in p.m?

 

[bbuck]

Should be the same for most people as the time released is to help with stomach issues. And it has to build up in the liver over time to be most effective.

 

[Southernjuice]

Probably gonna have many disagree here but...from someone who has HAD to take metformin for years. There are all natural ingredients that way out perform metformin and without the MANY nasty sides. Your speaking with a self-induced diabetic by lifestyle. Bodybuilder/Powerlifter turned Corp man= out of shape diabetic. I'm back in the iron pile and threw that metformin in the trash by taking what works. It's a combination of 1-3 items found in most households . No not selling anything just gotta jet at the moment. I would hate for anyone to take that med not knowing what I do about it.

 

[Southernjuice]

I started taking turmeric and cinnamon...I threw the metformin I'd been taking for years in the trash. That combination proved more powerful than the pharmaceuticals for me...it will vary per individual. It created more insulin sensitivity and within 4 days lowered my average GR by 60 points.

 

[Nightrider]

^^ interesting, I have never been able to tolerate met, may look into the 2 shops above.

 

[jamescb77]

No real difference to me I have used both the same


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